Silanized nucleic acids: a general platform for DNA immobilization

A self-assembled DNA nanostructure-amplified quartz crystal microbalance with dissipation biosensing platform for nucleic acids.

A self-assembled DNA nanostructure as an efficient signal amplifier was introduced to create a simple and label-free quartz crystal microbalance with dissipation monitoring (QCM-D) biosensing platform for highly sensitive and selective detection of nucleic acids.

Magnetic peptide nucleic acids for DNA targeting.

A versatile synthetic platform for the efficient immobilization of PNAs on magnetic iron oxides, providing magnetic nanosensors for selective DNA recognition, is presented.

IMMOBILIZATION OF MICROBIAL CELLS FOR THE PRODUCTION OF ORGANIC ACIDS

Techniques of immobilization of microbial- cells have been established by multifunctional reagents such as glutaraldehyed on a solid support. Immobilized cell reactor was designed to demonstrate stability of cross linking of whole cells for the production of organic acids. An eighty-six percent conversion of glucose was obtained for an eight hour retention time. The immobilized cell reacto...

Inhibition of a DNA-helicase by peptide nucleic acids.

Bis-peptide nucleic acid (bis-PNA) binding results in D-loop formation by strand displacement at complementary homopurine stretches in DNA duplexes. Transcription and replication in intact cells is mediated by multienzymatic complexes involving several proteins other than polymerases. The behaviour of the highly stable clamp structure formed by bis-PNAs has thus far been studied with respect to...

Molecular printboards as a general platform for protein immobilization: a supramolecular solution to nonspecific adsorption.